UFC 281: Adesanya vs. Pereira was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on November 12, 2022, at the Madison Square Garden in New York City, New York, United States. A UFC Middleweight Championship bout between current champion Israel Adesanya and former Glory Middleweight and Light Heavyweight Champion Alex Pereira headlined the event. The pairing previously met twice in kickboxing matchups. The first in April 2016 which Pereira won by unanimous decision. Their second meeting took place at Glory of Heroes 7 in March 2017, which Pereira won by third-round knockout.
Alex Pereira
Israel Adesanya
Zhang Weili
Carla Esparza
Dustin Poirier
Michael Chandler
Chris Gutiérrez
Frankie Edgar
Dan Hooker
Claudio Puelles
Renato Moicano
Brad Riddell
Ryan Spann
Dominick Reyes
Erin Blanchfield
Molly McCann
Andre Petroski
Wellington Turman
Matt Frevola
Ottman Azaitar
Karolina Kowalkiewicz
Silvana Gómez Juárez
Mike Trizano
Seung Woo Choi
Montel Jackson
Julio Arce
Carlos Ulberg
Nicolae Negumereanu