The PFL 2 mixed martial arts event for the 2021 season of the Professional Fighters League was held on April 29, 2021. This was the second regular season event of the tournament and included fights in the Welterweight and Light heavyweight divisions. The event was to be headlined by a welterweight clash between the former UFC title contender and Bellator welterweight champion Rory MacDonald and the former UFC veteran David Michaud.
Rory MacDonald
Curtis Millender
Ray Cooper III
Jason Ponet
Joao Zeferino
Gleison Tibau
Emiliano Sordi
Chris Camozzi
Antônio Carlos Júnior
Thomas Joseph Lawlor
Cezar Ferreira
Nick Roehrick
Sadibou Sy
Nikolai Aleksakhin
Marthin Hamlet
Dan Spohn