Mabel Byrne
(Jessica 'JeeJee' Santo)
Emily VanCamp
(Myriam Levy)
Jennifer Esposito
(Linda Santo)
Aidan Quinn
(Bishop Ryan)
Joshua Bowman
(Frank Belanger)
Ciaran Byrne
(Fr. Luke McAteer)
Robert Wahlberg
(Dr. Sam Bernard)
Jeff Wiens
(Dr. Tony Messina)
David Chiavaroli
(James Santo Jr.)
Jessica Galinas
(Natalie Comeau)
Heather Benson
(Pilgrim)