For Tammy, a burger-joint employee, a bad day keeps getting worse. She wrecks her car, loses her job and finds that her husband has been unfaithful. It's time for Tammy to hit the road, but without money or transportation, her options are limited. Her only choice is a road trip with her hard-drinking grandmother, Pearl, who has a car, cash and an itch to see Niagara Falls. It's not the escape Tammy had in mind, but it may be what she needs.
Melissa McCarthy
Susan Sarandon
Kathy Bates
Mark Duplass
Gary Cole
Sandra Oh
Allison Janney
Dan Aykroyd
Nat Faxon
Toni Collette
Sarah Baker
Rich Williams
Ben Falcone
Steve Little
Dakota Lee
Mark L. Young
Mia Rose Frampton
Steve Mallory
Big Al Hall
Jones Smith
Joe Baxter
Benjamin Chontos
Sean Gould
Keith Welborn
Oscar Gale
Justin Smith
Willie Hill
Zach Hanner
Jason Vail
Leon Lamar
Larry Dorf
Ricky Muse
Barbara Weetman
William Flaman
Rey Hernandez
Penn Holderness
Michelle Li
Raven Angeline Whisnant
Damon Jones
Sandy McCarthy
Margo Passas
Sheila Brothers
J.R. Rodriguez
Michelle Rivera Huckaby
Rob Springer
Cricket Ellis
Kaitlyn Christian
David Andrew Nash