Set 15 years after "Twentieth Century Boys," Kanna (Airi Taira) reunites with several main characters from the first film in an attempt to stop Friend's increasing influence over the world and continued plans to eliminate humanity, as detailed in the New Book of Prophecy.
Toshiaki Karasawa
Etsushi Toyokawa
Takako Tokiwa
Airi Taira
Nana Katase
Hitomi Kuroki
Eiko Koike
Haruka Kinami
Yoji Tanaka
Andrew Koji
Arata Iura
Teruyuki Kagawa
Fumiyo Kohinata