FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.
Samuel L. Jackson
Julianna Margulies
Nathan Phillips
Kenan Thompson
Rachel Blanchard
Flex Alexander
Keith Dallas
Sunny Mabrey
Lin Shaye
Elsa Pataky
Bruce James
Casey Dubois
Gerard Plunkett
Terry Chen
Emily Holmes
Mark Houghton
David Koechner
Bobby Cannavale
Yan-Kay Crystal Lowe
Todd Louiso
Kendall Cross
Samantha McLeod
Ann Warn Pegg
Taylor Kitsch
Kevin McNulty
Agam Darshi
Lisa Marie Caruk
Mi-Jung Lee
Lesley Aletter
Byron Lawson
Tom Butler