50/50

It takes a pair to beat the odds.

Inspired by a true story, a comedy centered on a 27-year-old guy who learns of his cancer diagnosis and his subsequent struggle to beat the disease.

Comedy Drama

Joseph Gordon-Levitt

(Adam Lerner)

Seth Rogen

(Kyle Hirons)

Anna Kendrick

(Katherine McKay)

Bryce Dallas Howard

(Rachael)

Anjelica Huston

(Diane Lerner)

Serge Houde

(Richard Lerner)

Philip Baker Hall

(Alan)

Matt Frewer

(Mitch)

Andrew Airlie

(Dr. Ross)

Peter Kelamis

(Phil)

Jessica Parker Kennedy

(Jackie)

Sugar Lyn Beard

(Susan)

Donna Yamamoto

(Dr. Walderson)

Yee Jee Tso

(Dr. Lee)

Sarah Smyth

(Jenny)

Daniel Bacon

(Dr. Phillips)

P. Lynn Johnson

(Bernie)

Laura Bertram

(Claire)

Matty Finochio

(Ted)

Marie Avgeropoulos

(Allison)

Luisa d'Oliveira

(Agabelle Loogenburgen)

Veena Sood

(Nurse Stewart)

Andrea Brooks

(Attractive Woman #2)

Beatrice King

(Pretty Girl)

Chilton Crane

(Mother on the Bus)

Lauren Miller Rogen

(Bodie)

Jason Vaisvila

(Cute Guy with Dreads)

Brent Sheppard

(Minister)

Stephanie Belding

(Friendly Nurse)

Ryan W. Smith

(Joe)

William 'Big Sleeps' Stewart

(George)

Amitai Marmorstein

(Young Person on the Bus)

Will Reiser

(Greg)

Christopher De-Schuster

(Art Gallery Patron)

Adrian Glynn McMorran

(Bartender)

Karen van Blankenstein

(Nurse Scott)

Richard C. Burton

(Thom the Patient)

Susan De West

(Bar Girl)

Neil Corbett

(Hospital Tech)

Stephen Colbert

(Self (archive footage) (uncredited))

D. C. Douglas

(Live Volcano Reporter (voice) (uncredited))

Cameron K. Smith

(Chemo Patient (uncredited))

Tom MacNeill

(Office Staff (uncredited))