After winning over the staff and students of Milford High School, chemistry teacher Richard Martinez aka Bianca Del Rio sent her nemesis Vice Principal Deborah “Debbie” Ward to jail in a flawlessly executed plan. When Debbie is released from jail, she conjures up a scheme to do away with Bianca Del Rio once and for all, by luring her on a dangerous journey to Russia to accept a teaching award and cash prize.
Bianca Del Rio
Rachel Dratch
Katya Zamolodchikova
Sally Jessy Raphael
Jason Bellini
Itay Hod
Denton Blane Everett
Téa Mckay
Michael Musto
Alyssa Edwards
Molly Ryman
Chagmion Antoine
Kaleb King
Sean Anglin
Wanda Sykes
Joe Ando-Hirsh
D.J. 'Shangela' Pierce
Doug Plaut
Alicia Goranson
Heather McDonald
Alaska Thunderfuck
Nicole Gemma
Trina Shpur
Cheyenne Jackson
Kristen Johnston
Dot-Marie Jones
Debbie Troche
Brian Nemiroff
Corey Legendre
Addison LeMay
Michael Joseph Murray
Victor Riffel
Darienne Lake
Joey Navedo
Sandra Rodriguez
Chris Matesevac
Jiggly Caliente
Lady Bunny
Mrs. Kasha Davis
Michael Fitzgerald
Serge Didenko
Deborah Unger
Peter Daniel Straus
Jasson Finney
Filip Lacina
Janeane Garofalo
Matthew Camp
Steven Nalley
Adam Cloninger
David Granados
Bianca Leigh
Jennie Eps
Sara Harman
Alexandria Watts
James Zeiss