Puppy mayhem turns the lives of newlywed Chihuahua parents Papi and Chloe upside down when their rambunctious, mischievous puppies present one challenge after another. But when their human owners end up in trouble, the tiny pups will stop at nothing to save them - because in good times and hard times, the family always sticks together. So Papi, Chloe and the puppies embark on a heroic adventure, proving once again that big heroes come in small packages.
Odette Annable
George Lopez
Zachary Gordon
Christine Lakin
Miguel Ferrer
Madison Pettis
Bridgit Mendler
Jon Donahue
Phill Lewis
Delaney Jones
Tom Kenny
Loretta Devine
Alyssa Milano
Jon Huertas
Marcus Coloma
Erin Cahill
Susan Blakely
Lupe Ontiveros
Castulo Guerra
Rance Howard
Elaine Hendrix
Brian Stepanek
French Stewart
Morgan Fairchild
Emily Osment
Ernie Hudson