After healing the leg of the murderer John Wilkes Booth, responsible for the assassination of President Abraham Lincoln, perpetrated on April 14, 1865, during a performance at Ford's Theatre in Washington; Dr. Samuel A. Mudd, considered part of the atrocious conspiracy, is sentenced to life imprisonment and sent to the sinister Shark Island Prison.
Warner Baxter
Gloria Stuart
Claude Gillingwater
Arthur Byron
O. P. Heggie
Harry Carey
Francis Ford
John McGuire
Francis McDonald
Douglas Wood
John Carradine
Joyce Kay
Fred Kohler Jr.
Ernest Whitman
Paul Fix
Frank Shannon
Frank McGlynn Sr.
Leila McIntyre
Etta McDaniel
J.M. Kerrigan
Arthur Loft
Paul McVey
Maurice Murphy
Matthew Beard