The Guilt Trip

Get ready for one mother of a road trip.

An inventor and his mom hit the road together so he can sell his latest invention.

Comedy

Seth Rogen

(Andy Brewster)

Barbra Streisand

(Joyce Brewster)

Yvonne Strahovski

(Jessica)

Colin Hanks

(Rob)

Brett Cullen

(Ben)

Adam Scott

(Andrew Margolis Jr.)

Ari Graynor

(Joyce Margolis)

Kathy Najimy

(Gayle)

Danny Pudi

(Sanjay)

Casey Wilson

(Amanda)

Dale Dickey

(Tammy)

Brandon Keener

(Ryan Mcfee)

Robert Curtis Brown

(Bob Ferguson)

Nora Dunn

(Amy)

Miriam Margolyes

(Anita)

Rose Abdoo

(Diana)

Analeis Lorig

(Moonlight)

Gabrielle Gumbs

(Stripper)

Rick Gonzalez

(Mark)

Worth Howe

(Bob)

Vicki Goldsmith

(Young Joyce)

Constance Esposito

(HSN Executive)

Creed Bratton

(Suitor)

Jeff Kober

(Jimmy)

Tom Virtue

(Mature Singles Man)

John Funk

(K-Mart Executive)

Julene Renee

(K-Mart Receptionist (as Julene Renee-Preciado))

Matthew Levinson

(Toddler Andy)

Vivian Vanderwerd

(Mature Singles Woman)

Zabryna Guevara

(K-Mart Executive)

Michael Cassidy

(Fake Andy (uncredited))