When Kentucky plantation owner George Shelby is forced to sell several of his slaves, one of them, Eliza Harris, escapes across the icy Ohio River with her child. Kindly old Uncle Tom, however, is sold to a Southern slave trader and begins his voyage down the Mississippi River. During the trip, he rescues little Eva St. Clair from the river, and out of gratitude, the girl's father buys him.
Marguerite Clark
Sam Hardy
Jack W. Johnston
Florence Carpenter
Frank Losee
Phil Ryley
Harry Lee
Walter P. Lewis
Augusta Anderson
Ruby Hoffman
Susanne Willis
Mrs. Priestly Morrison
Thomas Carnahan Jr.
Jere Austin
Henry Stanford
Chester Conklin