Zhang Ming'en graduated from the prestigious Central Academy of Drama. During his school and early college days, he participated in some short films and a sitcom's bit part before officially debuting in 2016 with a memorable role as Adjutant Zhang Rishan in the tomb-raiding series The Mystic Nine. He went on to star in a spin-off of the series titled Tiger Bones Plum Blossom, which focuses on his character.[3] In 2017, he acted in a highly acclaimed mystery fantasy web drama, Tientsin Mystic. In 2018, Zhang reprised his role in the spin-off to The Mystic Nine, Tomb of the Sea. His performance was well-received by viewers and received acclaim. He was cast as the male protagonist for the first time in the romance supernatural drama, Destiny's Love. In 2019, Zhang starred in the television series Nice to Meet You, the sequel to the 2017 hit drama Because of You. The same year, he starred in fantasy drama L.O.R.D. Critical World.
老九門番外之虎骨梅花
In Search of Lost Time
(Du Yi)
The Mystic Nine Side Story: Tiger Bones Plum Blossom
(张副官)
Tientsin Mystic
(Ding Mao)
The Mystic Nine
(Lieutenant Zhang)
Eternal Brotherhood
(Siyi Lin)
Nice To Meet You
(Yu Zhi / James)
Destiny's Love
(Chi Yu)
L.O.R.D. Critical World
(Zero (Qi Ling, Disciple to the 7th degree))
Insect Totem
(Pan Jun)
Tomb of the Sea
(Zhang Rishan)
Sweet Tasks
Meeting Mr. Right
Scent of Time
(Jin Lin)
The Land of Warriors
(Xue Qinghe)