Richard Gutierrez
(Vergel / Kamandag)
Mark Anthony Fernandez
(Lucero Serrano / Talim)
Jewel Mische
(Jenny)
Maxene Magalona
(Lily)
Ehra Madrigal
(Ditas / Denise / Lady Kamandag)
Eula Valdez
(Alicia)
Glaiza de Castro
(Alicia (young))
Johnny Delgado
(Budol)
Zoren Legaspi
(Gulag)
Ariel Rivera
(Abdon Serrano)
Ronaldo Valdez
(Pepe)
Ramon Christopher
(Pepe (young))
Francine Prieto
(Kuran)
Rainier Castillo
(Ikoy)
Francis Magundayao
(Boyong / Dagok)
Melissa Mendez
(Elena)
Benjie Paras
(Dinggol)
Sunshine Dizon
(Ragona)