After breaking up with her girlfriend, a nightclub singer, Jane, answers a personal ad from Robin, a real estate agent with AIDS, seeking a cross-country travel partner. On their journey from New York City to Los Angeles, the two stop by Pittsburgh to pick up Jane's friend Holly, who is trying to escape an abusive relationship. With three distinct personalities, the women must overcome their differences to help one another.
Whoopi Goldberg
Mary-Louise Parker
Drew Barrymore
Matthew McConaughey
James Remar
Billy Wirth
Jude Ciccolella
Dennis Boutsikaris
Estelle Parsons
Amy Aquino
Lori Alan
Anita Gillette
Stan Egi
Stephen Gevedon
Amy Ray
Emily Saliers
Gedde Watanabe
Jon Seda
Mimi Toro
Mary Anne McGarry
Michael Storm
Danielle Shuman
Julian Neil
Niecy Nash-Betts
Ted Zurkowski
Jill C. Klein
Marnie Crossen
Aaron Lustig
Terri White
George Georgiadis
Cheryl A. Kelly
Adria Contreras
Malika Edwards
Pablo Espinosa
Kevin La Presle
John F. Manfredonia
James Shuffield
Thomas Kevin Danaher
Richard Lowell McDole
Don Hewitt Sr.
Andy Duppin
Alan Mirikitani
Joe Pyles
Worthy Davis
Joshua Segal
Breta La Von
Patrice Jones
Tito Larriva
Gary Montemer
Vernon Francisco
Joseph Alfieri
Fidelis Manuel
Sylvester Oliver
Benedict Martinez